Aspirin, hydroxychloroquine, and hepatic enzyme abnormalities with methotrexate in rheumatoid arthritis
نویسندگان
چکیده
منابع مشابه
Methotrexate, hydroxychloroquine, and intramuscular gold in rheumatoid arthritis.
OBJECTIVE The use of disease modifying antirheumatic drugs (DMARD) for rheumatoid arthritis (RA) is predicated on the expected value of the treatment course. Most clinical data are generalized from randomized controlled trials (RCT), which may result in estimates that are discordant with clinical experience and cannot address the effects of sequence of drugs. We computed estimates of relative D...
متن کاملLiver Toxicity in Rheumatoid Arthritis Patients Treated With Methotrexate
Background:Methotrexate (MTX) is one of the most commonly used disease-modifying antirheumatic drugs in the treatment of rheumatoid arthritis (RA) which can be associated with toxic effects on different organs. This study was designed to investigate the hepatotoxic effects in RA patients treated with MTX. Methods: In this cross-sectional observational study, RA patients who received standard d...
متن کاملA study of rheumatoid arthritis management with the triple combination of methotrexate + hydroxychloroquine + sulfasalazine and double combination of methotrexate + hydroxychloroquine
Rheumatoid arthritis is chronic multisystem disease, failure rate with monotherapy is high. The present study was designed to compare the efficacy and safety of triple combination of Methotrexate + Hydroxychloroquine + Sulfasalazine and double combination of Methotrexate + Hydroxychloroquine in patients suffering from Rheumatoid Arthritis. The present study was a prospective, randomized, single...
متن کاملAssessment of hepatic fibrosis by transient elastography in rheumatoid arthritis patients receiving methotrexate
Background and Aim: Methotrexate (MTX) is commonly used in the treatment of diseases such as rheumatoid arthritis (RA) but, its hepatotoxicity potential, always has been a major concern. The aim of this study is to determine the rate of liver fibrosis by transient elastography (TE) method and its relationship with cumulative dose of MTX and duration of treatment, in rheumatoid arthritis patient...
متن کاملmethotrexate hepatotoxicity in patients with rheumatoid arthritis
background increases in aminotransferases (transaminitis) are potential major adverse reactions seen with long-term use of methotrexate (mtx). the aim of this study, therefore was to evaluate the incidence of mtx induced hepatotoxicity and its risk factors among rheumatoid arthritis (ra) patients. methods this retrospective study described 286 patients with ra who received ≤ 7.5 mg mtx weekly...
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ژورنال
عنوان ژورنال: Arthritis & Rheumatism
سال: 1990
ISSN: 0004-3591,1529-0131
DOI: 10.1002/art.1780331102